abstract：OBJECT:Approximately 25% of patients exhibit cognitive dysfunction 24 hours after carotid endarterectomy (CEA). One of the purported mechanisms of early cognitive dysfunction (eCD) is hypoperfusion due to inadequate collateral circulation during cross-clamping of the carotid artery. The authors assessed whether poor co...

journal_title：Journal of neurosurgery

authors： Sussman ES,Kellner CP,Mergeche JL,Bruce SS,McDowell MM,Heyer EJ,Connolly ES

更新日期：2014-09-01 00:00:00

abstract：OBJECT:Pituitary tumors are abnormal growths that develop in the pituitary gland. The Central Brain Tumor Registry of the United States (CBTRUS) contains the largest aggregation of population-based data on the incidence of primary CNS tumors in the US. These data were used to determine the incidence of tumors of the pi...

journal_title：Journal of neurosurgery

authors： Gittleman H,Ostrom QT,Farah PD,Ondracek A,Chen Y,Wolinsky Y,Kruchko C,Singer J,Kshettry VR,Laws ER,Sloan AE,Selman WR,Barnholtz-Sloan JS

更新日期：2014-09-01 00:00:00

abstract：OBJECT:The nitric oxide system has been linked to the pathogenesis of aneurysmal subarachnoid hemorrhage (SAH). The authors performed a case-control study to investigate the association between SAH and common genetic variants within the endothelial nitric oxide synthase gene (NOS3). METHODS:Three hundred thirty-three ...

journal_title：Journal of neurosurgery

authors： Staalsø JM,Edsen T,Kotinis A,Romner B,Springborg JB,Olsen NV

更新日期：2014-09-01 00:00:00

abstract：OBJECT:Endothelial tight junction (TJ) expression is mostly absent in cerebral cavernous malformations (CMs), which causes increased perilesional erythrocyte and fluid oozing. However, in a subset of CM lesions, foci of preserved TJ staining are observed along endothelial cell contacts. The clinical relevance of this f...

journal_title：Journal of neurosurgery

authors： Jakimovski D,Schneider H,Frei K,Kennes LN,Bertalanffy H

更新日期：2014-09-01 00:00:00

abstract：OBJECT:The aim of this paper was to validate the diffusion tensor imaging (DTI) model for delineation of the corticospinal tract using cortical and subcortical white matter electrical stimulation for the location of functional motor pathways. METHODS:The authors compare probabilistic versus deterministic DTI fiber tra...

journal_title：Journal of neurosurgery

authors： Mandelli ML,Berger MS,Bucci M,Berman JI,Amirbekian B,Henry RG

更新日期：2014-08-01 00:00:00

abstract：OBJECT:There is increasing evidence that simulation provides high-quality, time-effective training in an era of resident duty-hour restrictions. Simulation may also permit trainees to acquire key skills in a safe environment, important in a specialty such as neurosurgery, where technical error can result in devastating...

journal_title：Journal of neurosurgery

authors： Kirkman MA,Ahmed M,Albert AF,Wilson MH,Nandi D,Sevdalis N

更新日期：2014-08-01 00:00:00

abstract：OBJECT:Transclival endoscopic endonasal surgery (EES) has recently been used for the treatment of posterior fossa tumors. The optimal method of reconstruction of large clival defects following EES has not been established. METHODS:A morphometric analysis of the posterior fossa was performed in patients who underwent t...

journal_title：Journal of neurosurgery

authors： Koutourousiou M,Filho FV,Costacou T,Fernandez-Miranda JC,Wang EW,Snyderman CH,Rothfus WE,Gardner PA

更新日期：2014-08-01 00:00:00

abstract：OBJECT:The aim of this study was to describe the similarity of configuration between the arachnoid complex in the posterior half of the incisural space and the Liliequist membrane. METHODS:Microsurgical dissection and anatomical observation were performed in 20 formalin-fixed adult cadaver heads. The origin, distribut...

journal_title：Journal of neurosurgery

authors： Zhang XA,Qi ST,Fan J,Huang GL,Peng JX

更新日期：2014-08-01 00:00:00

abstract：OBJECT:Using a database that enabled longitudinal follow-up, the authors assessed the long-term outcomes of unruptured cerebral aneurysms repaired by clipping or coiling. METHODS:An observational analysis of the California Office of Statewide Health Planning and Development (OSHPD) database, which follows patients lon...

journal_title：Journal of neurosurgery

authors： Gonda DD,Khalessi AA,McCutcheon BA,Marcus LP,Noorbakhsh A,Chen CC,Chang DC,Carter BS

更新日期：2014-06-01 00:00:00

abstract：OBJECT:Glioblastoma is the most aggressive malignant brain tumor, and overall patient survival has not been prolonged even by conventional therapies. Previously, the authors found that chemically synthesized glycans could be anticancer agents against growth of a series of cancer cells. In this study, the authors examin...

journal_title：Journal of neurosurgery

authors： Faried A,Arifin MZ,Ishiuchi S,Kuwano H,Yazawa S

更新日期：2014-06-01 00:00:00

abstract：:The goals of the present study were to demonstrate the ability of high-resolution ultrasonography to delineate normal nerve fascicles within or around peripheral nerve sheath tumors (NSTs). A blinded examiner evaluated 2 patients with symptomatic upper limb NSTs with high-resolution ultrasonography performed in the pe...

journal_title：Journal of neurosurgery

authors： Simon NG,Cage T,Narvid J,Noss R,Chin C,Kliot M

更新日期：2014-05-01 00:00:00

abstract：OBJECT:Until now there has been no reliable stimulation protocol for inducing transient language disruptions while mapping Broca's area. Despite the promising data of only a few studies in which speech arrest and language disturbances have been induced, certain concerns have been raised. The purpose of this study was t...

journal_title：Journal of neurosurgery

authors： Rogić M,Deletis V,Fernández-Conejero I

更新日期：2014-05-01 00:00:00

abstract：OBJECT:This study details the extent of resection and complications associated with endonasal endoscopic surgery for pituitary tumors invading the cavernous sinus (CS) using a moderately aggressive approach to maximize extent of resection through the medial CS wall while minimizing the risk of cranial neuropathy and bl...

journal_title：Journal of neurosurgery

authors： Woodworth GF,Patel KS,Shin B,Burkhardt JK,Tsiouris AJ,McCoul ED,Anand VK,Schwartz TH

更新日期：2014-05-01 00:00:00

abstract：OBJECT:Hospital readmission within 30 days of discharge is a major contributor to the high cost of health care in the US and is also a major indicator of patient care quality. The purpose of this study was to investigate the incidence, causes, and predictors of 30-day readmission following craniotomy for malignant supr...

journal_title：Journal of neurosurgery

authors： Marcus LP,McCutcheon BA,Noorbakhsh A,Parina RP,Gonda DD,Chen C,Chang DC,Carter BS

更新日期：2014-05-01 00:00:00

abstract：OBJECT:Neurocan is a major form of growth-inhibitory molecule (growth-IM) that suppresses axonal regeneration after neural injury. Bone marrow stromal cells (MSCs) have been shown to inhibit neurocan expression in vitro and in animal models of cerebral ischemia. Therefore, the present study was designed to investigate ...

journal_title：Journal of neurosurgery

authors： Mahmood A,Wu H,Qu C,Mahmood S,Xiong Y,Kaplan DL,Chopp M

更新日期：2014-05-01 00:00:00

abstract：OBJECT:After complete resection and radiation therapy, the 10-year overall survival rates for adult patients with posterior fossa ependymomas approach 85%. This favorable outcome profile emphasizes the critical importance of functional preservation to this patient population. Here, the authors identify predictors of fu...

journal_title：Journal of neurosurgery

authors： Mirzadeh Z,Bina R,Kusne Y,Coons SW,Spetzler RF,Sanai N

更新日期：2014-05-01 00:00:00

abstract：OBJECT:It is assumed that the observed increase in brain tumor incidence may at least partially be explained by increased use of MRI. However, to date no direct estimate of this effect is available. The authors undertook this registry-based study to examine whether regional frequencies of cerebral MRI use correlate to ...

journal_title：Journal of neurosurgery

authors： Solheim O,Torsteinsen M,Johannesen TB,Jakola AS

更新日期：2014-04-01 00:00:00

abstract：OBJECT:Traumatic parenchymal mass lesions are common sequelae of traumatic brain injuries (TBIs). They occur in up to 8.2% of all TBI cases and 13%-35% of severe TBI cases, and they account for up to 20% of surgical intracranial lesions. Controversy exists concerning the association between radiological and clinical ev...

journal_title：Journal of neurosurgery

authors： Iaccarino C,Schiavi P,Picetti E,Goldoni M,Cerasti D,Caspani M,Servadei F

更新日期：2014-04-01 00:00:00

abstract：OBJECT:Cerebral vasospasm following subarachnoid hemorrhage (SAH) causes significant morbidity in a delayed fashion. The authors recently published a new scale that grades the maximum thickness of SAH on axial CT and is predictive of vasospasm incidence. In this study, the authors further investigate whether different ...

journal_title：Journal of neurosurgery

authors： Abla AA,Wilson DA,Williamson RW,Nakaji P,McDougall CG,Zabramski JM,Albuquerque FC,Spetzler RF

更新日期：2014-02-01 00:00:00

abstract：OBJECT:An extensive craniopharyngioma is a tumor that extends into multiple compartments (subarachnoid spaces) and attains a size larger than 4 cm. A wide spectrum of approaches and strategies has been used for resection of such craniopharyngiomas. In this report the authors focused on the feasibility and efficacy of m...

journal_title：Journal of neurosurgery

authors： Gerganov V,Metwali H,Samii A,Fahlbusch R,Samii M

更新日期：2014-02-01 00:00:00

abstract：OBJECT:Retrochiasmatic craniopharyngiomas are surgically challenging tumors. Retrochiasmatic craniopharyngiomas with complicated conditions such as large diameter, major calcification, or significant extension to the third ventricle or posterior fossa present surgical challenges; moreover, recurrent retrochiasmatic cra...

journal_title：Journal of neurosurgery

authors： Kunihiro N,Goto T,Ishibashi K,Ohata K

更新日期：2014-01-01 00:00:00

abstract：:The treatment of craniospinal war wounds proved to be a significant driving force in the early growth of neurosurgery as a specialty. This publication explores the historical relationship between the evolution of combat methodology from antiquity through modern conflicts as it dovetails with and drives corresponding a...

journal_title：Journal of neurosurgery

authors： Dowdy J,Pait TG

更新日期：2014-01-01 00:00:00

abstract：OBJECT:The authors' objective was 2-fold: 1) to compare outcomes of microsurgical resection for vestibular schwannoma (VS) between patients aged 70 years or older and patients younger than 70 years and 2) to test the hypothesis that symptomatic tumors in elderly patients represent a more aggressive variant of VS than t...

journal_title：Journal of neurosurgery

authors： Van Abel KM,Carlson ML,Driscoll CL,Neff BA,Link MJ

更新日期：2014-01-01 00:00:00

abstract：OBJECT:Cushing's disease is a challenging neuroendocrine disorder. Although resection remains the primary treatment option for most patients, the disease persists if there is residual or recurrent tumor. Stereotactic radiosurgery has been used to treat patients with persistent Cushing's disease after a prior resection....

journal_title：Journal of neurosurgery

authors： Sheehan JP,Xu Z,Salvetti DJ,Schmitt PJ,Vance ML

更新日期：2013-12-01 00:00:00

abstract：OBJECT:Recurrent malignant gliomas have inherent resistance to traditional chemotherapy. Novel therapies target specific molecular mechanisms involved in abnormal signaling and resistance to apoptosis. The proteasome is a key regulator of multiple cellular functions, and its inhibition in malignant astrocytic lines cau...

journal_title：Journal of neurosurgery

authors： Bota DA,Alexandru D,Keir ST,Bigner D,Vredenburgh J,Friedman HS

更新日期：2013-12-01 00:00:00

abstract：OBJECT:Atypical meningioma often recurs even after resection. As a salvage modality, radiotherapy or stereotactic radiosurgery (SRS) is attempted for this aggressive tumor. This retrospective study was performed to evaluate the efficacy of SRS that involved Gamma Knife surgery (GKS) for atypical meningioma. METHODS:Th...

journal_title：Journal of neurosurgery

authors： Hanakita S,Koga T,Igaki H,Murakami N,Oya S,Shin M,Saito N

更新日期：2013-12-01 00:00:00

abstract：:Fat embolism syndrome (FES) is a common clinical entity that can occasionally have significant neurological sequelae. The authors report a case of cerebral fat embolism and FES that required surgical management of intracranial pressure (ICP). They also discuss the literature as well as the potential need for neurosurg...

journal_title：Journal of neurosurgery

authors： Kellogg RG,Fontes RB,Lopes DK

更新日期：2013-11-01 00:00:00

abstract：OBJECT:The goals of this study were to report the clinical presentation, radiographic findings, operative strategy, and outcomes among patients with temporal bone encephaloceles and cerebrospinal fluid fistulas (CSFFs) and to identify clinical variables associated with surgical outcome. METHODS:A retrospective case se...

journal_title：Journal of neurosurgery

authors： Carlson ML,Copeland WR 3rd,Driscoll CL,Link MJ,Haynes DS,Thompson RC,Weaver KD,Wanna GB

更新日期：2013-11-01 00:00:00

abstract：OBJECT:The authors performed a study to review outcomes following Gamma Knife radiosurgery for cerebral arteriovenous malformations (AVMs) and to create a practical scale to predict long-term outcome. METHODS:Outcomes were reviewed in 1012 patients who were followed up for more than 2 years. Favorable outcome was defi...

journal_title：Journal of neurosurgery

authors： Starke RM,Yen CP,Ding D,Sheehan JP

更新日期：2013-10-01 00:00:00

abstract：OBJECT:The objective of the present study was to perform a prospective evaluation of the potential efficacy and safety of intraoperative photodynamic therapy (PDT) using talaporfin sodium and irradiation using a 664-nm semiconductor laser in patients with primary malignant parenchymal brain tumors. METHODS:In 27 patie...

journal_title：Journal of neurosurgery

authors： Muragaki Y,Akimoto J,Maruyama T,Iseki H,Ikuta S,Nitta M,Maebayashi K,Saito T,Okada Y,Kaneko S,Matsumura A,Kuroiwa T,Karasawa K,Nakazato Y,Kayama T

更新日期：2013-10-01 00:00:00

abstract：OBJECT:There is no description of the change in the posterior cerebral artery (PCA) in the diagnostic criteria of moyamoya disease (MMD). However, PCAs are often involved in the clinical setting, and an understanding of the significance of PCA lesions is therefore of great importance when evaluating the disease progres...

journal_title：Journal of neurosurgery

authors： Hishikawa T,Tokunaga K,Sugiu K,Date I

更新日期：2013-10-01 00:00:00

abstract：OBJECT:Patients with subarachnoid hemorrhage (SAH) and their close friends and family may be excessively fearful that the patient will have a recurrence, and such fears could play a critical role in the poor recovery shown by many patients The authors examined whether these fears could account for significant variance ...

journal_title：Journal of neurosurgery

authors： Covey J,Noble AJ,Schenk T

更新日期：2013-10-01 00:00:00

abstract：OBJECT:Although traumatic brain injury (TBI) is the leading cause of death and morbidity in young adults, no effective pharmaceutical treatment is available. By inhibiting glycogen synthase kinase-3 (GSK-3) and histone deacetylases (HDACs), respectively, lithium and valproate (VPA) have beneficial effects in diverse ne...

journal_title：Journal of neurosurgery

authors： Yu F,Wang Z,Tanaka M,Chiu CT,Leeds P,Zhang Y,Chuang DM

更新日期：2013-09-01 00:00:00

abstract：OBJECT:Prior attempts to define normal cerebellar tonsil position have been limited by small numbers of patients precluding analysis of normal distribution by age group. The authors' objective in the present study was to analyze cerebellar tonsil location in every age range. METHODS:Two thousand four hundred patients ...

journal_title：Journal of neurosurgery

authors： Smith BW,Strahle J,Bapuraj JR,Muraszko KM,Garton HJ,Maher CO

更新日期：2013-09-01 00:00:00

abstract：OBJECT:Stereotactic radiosurgery (SRS) is an important treatment option for patients with cavernous sinus meningiomas (CSM). To analyze factors associated with local tumor control and complications after single-fraction SRS, the authors reviewed cases involving patients treated with Gamma Knife SRS between 1990 and 200...

journal_title：Journal of neurosurgery

authors： Pollock BE,Stafford SL,Link MJ,Garces YI,Foote RL

更新日期：2013-09-01 00:00:00

abstract：OBJECT:The direct thrombin inhibitor dabigatran has recently been approved in the US as an alternative to warfarin. The lack of guidelines, protocols, and an established specific antidote to reverse the anticoagulation effect of dabigatran potentially increases the rates of morbidity and mortality in patients with clos...

journal_title：Journal of neurosurgery

authors： Parra MW,Zucker L,Johnson ES,Gullett D,Avila C,Wichner ZA,Kokaram CR

更新日期：2013-09-01 00:00:00

abstract：:The authors present the case of a 20-year-old man who, 3 months after his initial injury, underwent repair of a 1.7-cm defect of the ulnar nerve at the wrist; repair was performed with an acellular nerve allograft. Given the absence of clinical or electrophysiological recovery at 8 months postrepair, the patient under...

journal_title：Journal of neurosurgery

authors： Berrocal YA,Almeida VW,Levi AD

更新日期：2013-09-01 00:00:00

abstract：OBJECT:Descriptions of visual dysfunction in pineal gland tumors tend to focus on upward gaze palsy alone. The authors aimed to characterize the nature, incidence, and functional significance of ophthalmological dysfunction after resection of tumors based on the pineal gland. METHODS:Review of a retrospective case ser...

journal_title：Journal of neurosurgery

authors： Hart MG,Sarkies NJ,Santarius T,Kirollos RW

更新日期：2013-08-01 00:00:00

abstract：OBJECT:Accurate diagnosis of the topographical relationships of craniopharyngiomas (CPs) involving the third ventricle and/or hypothalamus remains a challenging issue that critically influences the prediction of risks associated with their radical surgical removal. This study evaluates the diagnostic accuracy of MRI to...

journal_title：Journal of neurosurgery

authors： Pascual JM,Prieto R,Carrasco R,Barrios L

更新日期：2013-08-01 00:00:00

abstract：OBJECT:At present, the administration of prophylactic antiepileptic medication following aneurysmal subarachnoid hemorrhage (SAH) is controversial, and the practice is heterogeneous. Here, the authors sought to inform clinical decision making by identifying factors associated with the occurrence of seizures following a...

journal_title：Journal of neurosurgery

authors： Ibrahim GM,Fallah A,Macdonald RL

更新日期：2013-08-01 00:00:00